Network Performance Monitor Startup Error

Cannot start SolarWinds Orion NPM Web Engine (OrionNPMWeb.Application).

Error Number -2147024770
006~ASP 0177~Server.CreateObject-Fehler~8007007e

You may need to rerun the SolarWinds Configuration Wizard.
Visit http://www.solarwinds.net/netperfmon/help/admin/Security for more detailed information.